Heart mitral valve disease (MVD) is a terminal illness which may afflict over half of all cavalier King Charles spaniels by the age of 5 years and nearly all Cavaliers by age 10 years. It is CKCSs' leading cause of death.
- More: Cavalier King Charles spaniel MVD
- Mitral valve disease breeding protocol
- A few words about pimobendan (Vetmedin)
- ACVIM cardiologists consensus statement
- Research news
- Find a cardiologist in the USA and Canada
- June 2016 -- Ohio State University's Lynette Cole still needs cavaliers with no hearing loss for a deafness study.
- June 2016 -- Ohio State University needs cavaliers for clinical study of Chiari-like malformation and syringomyelia.
- June 2016 -- Brazilian ophthalmologisty surgeons transplant lip salivary glands to dogs' inner eye lids to cure dry eye.
- June 2016 -- USA study finds small breed dogs in heart failure live 100+ days longer if treated by cardiologists.
- June 2016 -- Studies find that most published research findings are false and that most clinical research is not useful, with clinical evidence becoming an industry advertisement tool.
- June 2016 -- Study of six cavalier pregnancies shows average ovulation periods and progesterone concentrations.
- June 2016 -- In study of 54 cavaliers, cranio-cervical junction (CCJ) abnormalities fail to predict future SM symptoms.
- June 2016 -- Cavaliers are most common and youngest victims of ischaemic stroke in study of 23 affected dogs.
- June 2016 -- Allopurinol causes xanthinuria in dogs treated for leishmaniasis.
- June 2016 -- FDA approves an appetite stimulant for ill dogs which will not eat.
- June 2016 -- Researchers may have an explanation for why ACE-inhibitors often are ineffective in treating cavaliers prior to heart failure.
- June 2016 -- Tufts study of 43 dogs (9 CKCSs) shows median survival time in Stage D MVD is nearly a year.
- May 2016 -- Study of 41 cavaliers shows that bacterial infection is an unlikely cause of PSOM in CKCSs.
- May 2016 -- UK researchers find evidence that CM in cavaliers may be due to overall brain and skull size.
- May 2016 -- UK researchers find that phantom scratching in CM/SM-affected cavaliers is due to the location and size of the syrinx.
- May 2016 -- Cavaliers have high incidence of breast tumors and low incidence of mast cell tumors, in Japanese review.
- May 2016 -- UK neurological researchers test electronic von Frey aesthesiometer to measure SM-associated neuropathic pain in cavaliers.
- May 2016 -- UK study shows SM-affected cavaliers have more blood vessels and stiffer vessel walls adjacent to lateral ventricles.
- May 2016 -- British researchers summarize episodic falling syndrome in cavaliers.
- May 2016 -- Gene researchers find a POMC gene mutation in Labradors is associated with obesity and greater food motivation.
- April 2016 -- Researchers summarize pimobendan's adverse effects reported in dogs with mild mitral valve insufficiency.
- April 2016 -- Dutch government singles out cavaliers in a study asking "Are purebreds really less healthy than crossbreeds?"
- April 2016 -- OUR BLOG: OFA finally recognizes what mitral valve disease is all about.
- April 2016 -- OUR BLOG: A Giant Leap Backwards: Some USA cavalier breeders boycott posting health test clearances on the OFA website.
- April 2016 -- UK neurologist calls for study of whether furosemide can delay syrinx growth in cavaliers.
- March 2016 -- UK orthopods report CKCSs are over-represented for medial patella luxation.
- March 2016 -- Dr. Sheila Crispin announces a study of a genetic cause of corneal dystrophy in the CKCS.
- March 2016 -- Cancerous thymus is found in 6-month old cavalier.
- March 2016 -- Accidental mixed breeding of Griffon Bruxellois (GB) provides an experiment in reducing risk of Chiari-like malformation and syringomyelia.
- March 2016 -- Study shows that the heart x-ray and echo sedative dexmedetomidine can cause false diagnoses of MVD and heart enlargement.
- February 2016 -- ACVIM issues a Consensus Statement on treating dogs for seizures.
- February 2016 -- UK Kennel Club's 2014 Health Survey shows 10 years is the average lifespan of CKCSs.
- February 2016 -- Dental specialist Jan Bellows summarizes chronic ulcerative paradental stomatitis.
- February 2016 -- NC State's Kate Meurs researches causes of MVD in cavaliers.
- February 2016 -- Ohio State University's Lynette Cole is conducting study of cavaliers with no hearing loss.
- February 2016 -- UK researchers find cell changes are similar in cavaliers and mixed breeds with advanced MVD.
- February 2016 -- OUR BLOG: EPIC trial results are scheduled to be announced at the ACVIM Forum in Denver in June.
- January 2016 -- Pancreatic lesions were found in 51.9% of post-mortem samples of cavaliers in UK study.
- January 2016 -- Renal lesions were found in 52.2% of post-mortem samples of cavaliers in UK study.
- January 2016 -- US's Food & Drug Administration warns drug manufacturers to not market levothyroxine sodium drugs unapproved by FDA.
- January 2016 -- Japanese researchers find the right ventricular Tei-index (RVTX) "strongly correlated with early death in dogs with MMVD".
- January 2016 -- French researchers include two cavaliers in study of facial and vestibular neuropathy of unknown origin.
- January 2016 -- Researchers find heart enlargement in cases of MVD and DCM has disease-specific causes and not just volume overload.
- January 2016 -- Neurologist Cerda-Gonzalez finds a close association of atlantooccipital overlapping (AOO) in cavaliers with clinical signs of SM.
- January 2016 -- US Neurologist Rossmeisl finds PSOM, CM/SM, brachycephalic airway obstruction syndrome and laryngeal paralysis in a cavalier.
- January 2016 - UK study of epileptic dogs also finds attention-deficit/hyperactivity disorder (ADHD) behaviors, and that a ketogenic medium chain triglyceride diet (MCTD) improved the ADHD activities.
- January 2016 - A study including cavaliers finds CT myelography is 100% accurate in detecting the sites of intervertebral disc herniation lesions.
- December 2015 - Study shows that the severity of asymptomatic MVD shows no association with serum C-reactive protein concentrations.
- December 2015 - SM syrinx formation computer model discounts likelihood that cerebrospinal fluid abnormalities create syrinxes.
- December 2015 - Fluoxetine treatments successfully treat two CKCSs with episodic falling syndrome.
- December 2015 - Alaska has a board certified veterinary cardiologist -- Dr. Dawn Webber.
- December 2015 - Neurologist Jason King sums up Chiari-like malformation.
- December 2015 - UK vet schools need cavaliers for neck pain study.
- December 2015 - Could an implant prolong a dog's life after congestive heart failure? Read about the vagus nerve stimulation device.
- December 2015 - Dr. Josh Stern gives up on finding MVD-free cavaliers for genetic research.
- December 2015 - Danish research concludes levetiracetam was not effective as mono-therapy for idiopathic epilepsy.
- November 2015 - Neurologists summarize research status of episodic falling syndrome in cavaliers.
Veterinary specialists have designed breeding guidelines to eliminate early-onset mitral valve disease in cavalier King Charles spaniels.
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Syringomyelia (SM) is reported to be "very widespread" in the cavalier King Charles spaniel breed. Syringomyelia is a disorder of the brain and spinal cord, which may cause severe head and neck pain and possible paralysis.
- More: CKCS syringomyelia
- SM breeding protocol
- Research news
- Reduced rate MRI clinic locations
- MRI screening protocol for SM
- Find a neurologist in the USA and Canada
- Estimated Breeding Values (EBVs)
- "Pedigree Dogs Exposed"
- "Pedigree Dogs Exposed - Three Years On"
Hip dysplasia reportedly afflicts up to one out of every four cavalier King Charles spaniels. It is a genetic disease which can cause the dogs pain and debilitation.
Low blood platelet counts in cavaliers usually are not a health problem. Many veterinarians are misled by low platelet counts to wrongly diagnose anemia or other serious disorders.
The size and shape of its head can cause serious breathing problems for the cavalier King Charles spaniel. Elongated soft palates, stenotic nares, everted laryngeal saccules, and laryngeal collapse are inherited developmental defects in the breed.
Cavalier King Charles spaniels appear predisposed to develop cerebellar infarcts, or strokes.
Cavaliers are predisposed to a form of congenital deafness, which is present at birth, and also to a progressive hereditary hearing loss, which usually begins during puppyhood and worsens, or progresses, until the dog is completely deaf, usually between the ages of three and five years.
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