Heart mitral valve disease (MVD) is a terminal illness which may afflict over half of all cavalier King Charles spaniels by the age of 5 years and nearly all Cavaliers by age 10 years. It is CKCSs' leading cause of death.
- More: Cavalier King Charles spaniel MVD
- Mitral valve disease breeding protocol
- A few words about pimobendan (Vetmedin)
- ACVIM cardiologists consensus statement
- Research news
- Find a cardiologist in the USA and Canada
- May 2017 -- Cardiologist Mark Rishniw says "Not so fast!" in prescribing pimobendan to all heart-enlarged MVD dogs.
- May 2017 -- Dr. David Williams finds pain from corneal ulceration causes increased tear production and may mask dry eye.
- May 2017 -- Cardiologist Philip Fox claims EPIC Study makes echocardiography optional in prescribing pimobendan before heart failure.
- May 2017 -- Columbian researchers find a variation of gene COL1A2 may play a role in causing MVD in canines.
- May 2017 -- Detroit hospital physicians find Neladenoson may reverse hind leg weakness in dogs in heart failure.
- May 2017 -- Mayo Clinic engineers a designer natriuretic peptide to mediate kidney impairment by furosemide.
- May 2017 -- Synthetic BNP injections potentially can offset RAAS activation in dogs in CHF.
- May 2017 -- Nationwide insurance reports cavaliers and other brachycephalic breeds are more often affected by common health conditions.
- April 2017 -- Texas A&M cardiologists fine tune cardiac troponin I measurements of MVD progression.
- April 2017 -- Cavaliers are over-represented in UK survey of over-weight, less exercised dogs.
- April 2017 -- UK Kennel Club spokesman trashes the MVD Breeding Protocol.
- April 2017 -- Analysis of UK cavalier breeders' compliance with the MVD Breeding Protocol shows breeders' hypocrisy.
- April 2017 -- Inventors seek US patent for chronic pancreatitis drug camostat mesilate.
- April 2017 -- U. of Ga. pathologists find T-zone lymphoma in a cavalier King Charles spaniel.
- April 2017 -- CKCS with histiocytic sarcoma of his spleen has deceptive signs and pathology.
- April 2017 -- Brazilian researchers find a quality of life questionnaire can accurately predict approaching cardiac deaths of dogs.
- March 2017 -- Cummings School (Tufts) researchers need DM-affected dogs for an engineered adenovirus study.
- March 2017 -- Lung ultrasound exams can accurately diagnose early signs of pulmonary edema and may predict onset of congestive heart failure.
- March 2017 -- Slovenian researchers report correlations between NT-proBNP and CoQ10 concentrations in dogs receiving cardiac treatment.
- March 2017 -- Korean researchers find that serum homocysteine concentrations increase as MVD progresses in dogs.
- March 2017 -- Italian researchers find 70% raw beef diet bests dry kibble in producing healthy gut functions.
- March 2017 -- NEW TOPIC: Plants -- toxic, poisonous -- including the sago palm.
- March 2017 -- Thai researchers find long-term treatment of Stage B dogs with sildenafil (Viagra) prevented progression of MVD.
- March 2017 -- Japan's Masami Uechi reports 92% success rate in 600+ open heart surgeries for MVD.
- March 2017 -- OUR BLOG: Will general practice veterinarians cut corners to prematurely prescribe pimobendan to MVD-affected cavaliers?
- March 2017 -- Tricuspid valve replacement with cow or pig valves has significant complications.
- March 2017 -- 3-D echocardiograms show differences in shapes of mitral valves of MVD-affected dogs versus healthy dogs.
- February 2017 -- USA researchers find promising CSF biomaker for early diagnosis of degenerative myelopathy.
- February 2017 -- Austrian heart clinic offers mitral valve repair surgery on MVD-affected dogs in heart failure.
- February 2017 -- Serum proteins are found to be differentially expressed in cavaliers with MVD.
- February 2017 -- OUR BLOG: Does detecting heart failure in MVD-affected cavaliers matter anymore?
- February 2017 -- Japanese researchers find left atrium strain can predict heart failure in MVD-affected dogs.
- January 2017 -- Nutri-Plus Gel stimulates the appetite of a cavalier in Stage C mitral valve disease suffering severe weight loss.
- January 2017 -- Italian researchers find cavaliers as the main represented breed for nuclear glycogen inclusions in the stomach's gastric glands.
- January 2017 -- Dr. Borgarelli seeks cavaliers in heart failure for minimally invasive mitral valve repair.
- January 2017 -- UK study identifies characteristics that cause painful Chiari-like malformation and syringomyelia in cavaliers.
- January 2017 -- UK study uses MRI scan measurements of hindbrain and craniocervical junction angles and distances to compare Chihuahuas, Affenpinschers and cavaliers with and without syringomyelia.
- January 2017 -- Phenobarbital and potassium bromide are effective supplements to imepitoin treatment of idiopathic epilepsy.
- January 2017 -- N-terminal BNP predictions of MVD status get more complicated.
- January 2017 -- OUR BLOG: All that cavalier owners need to know about spironolactone.
- January 2017 -- UK Kennel Club reports 2013-2014 compliance rate with its CM/SM breeding protocol was 0.28%.
- January 2017 -- UK researchers rate successful medications for Episodic Falling Syndrome in CKCSs.
- January 2017 -- UK study of 8,860 cavaliers shows that MVD Breeding Protocol works but breeders' compliance was poor.
- December 2016 -- Whole genome, next generation sequencing detects new muscular dystrophy mutation in a cavalier.
- December 2016 -- Study shows healthy cavaliers' mitral valve structure differs markedly from other breeds.
- December 2016 -- OUR BLOG: Why do any veterinarians prescribe useless drugs to MVD-affected cavaliers before heart failure?
- December 2016 -- Tufts' researchers test mesenchymal stem cell (MSC) treatments to improve MVD-affected dogs in heart failure.
- December 2016 -- NEW PAGE: Anesthesia and Sedatives in the Cavalier King Charles Spaniel.
- December 2016 -- UK study finds that cavaliers' cardiac-caused syncope collapses have increased troponin concentrations.
- December 2016 -- Polish researchers find four cell markers signal left atrium enlargement in MVD-dogs.
- December 2016 -- NEW PAGE: Patent Ductus Arteriosus (PDA) and the Cavalier King Charles Spaniel.
- November 2016 -- NEW TOPIC: Inflammatory bowel disease (IBD) in the cavalier King Charles spaniel.
- November 2016 -- NEW TOPIC: Glaucoma in the cavalier King Charles spaniel.
- November 2016 -- Cavalier eye sizes are large for small dogs but fit in the medium dog group.
- November 2016 -- UK Kennel Club approves MVD testing scheme for cavaliers.
- November 2016 -- Cavaliers were 15+% of dogs with erosive immune-mediated polyarthritis (IMPA).
- November 2016 -- Electronic von Frey aesthesiometer (eVF) testing fails to distinguish pain levels in 70 cavaliers.
- November 2016 -- French study of 1,668 cavalier bitches shows birth, still-born, and post natal mortality rates.
- November 2016 -- Cavaliers with ventriculomegaly may also have normal pressure hydrocephalus.
- November 2016 -- To feed or not to feed the pancreatitis patient? Who knows?
- November 2016 -- Simon Swift calls for parents/ grandparents of UK show cavaliers to meet MVD breeding protocol -- only 4% of CKCSs have been meeting that protocol.
- November 2016 -- UK and US researchers investigate links between epilepsy, drug-resistance, and affective disorders.
- November 2016 -- Pig bladder grafts successfully return sight to two cavaliers with corneal ulcers.
- November 2016 -- Brazilian researchers use digital video imaging to determine eye blink rates in cavaliers.
Veterinary specialists have designed breeding guidelines to eliminate early-onset mitral valve disease in cavalier King Charles spaniels.
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Syringomyelia (SM) is reported to be "very widespread" in the cavalier King Charles spaniel breed. Syringomyelia is a disorder of the brain and spinal cord, which may cause severe head and neck pain and possible paralysis.
- More: CKCS syringomyelia
- SM breeding protocol
- Research news
- Reduced rate MRI clinic locations
- MRI screening protocol for SM
- Find a neurologist in the USA and Canada
- Use harnesses instead of leashes for CM/SM dogs
- Estimated Breeding Values (EBVs)
- "Pedigree Dogs Exposed"
- "Pedigree Dogs Exposed - Three Years On"
Hip dysplasia reportedly afflicts up to one out of every four cavalier King Charles spaniels. It is a genetic disease which can cause the dogs pain and debilitation.
Low blood platelet counts in cavaliers usually are not a health problem. Many veterinarians are misled by low platelet counts to wrongly diagnose anemia or other serious disorders.
The size and shape of its head can cause serious breathing problems for the cavalier King Charles spaniel. Elongated soft palates, stenotic nares, everted laryngeal saccules, and laryngeal collapse are inherited developmental defects in the breed.
Cavalier King Charles spaniels appear predisposed to develop cerebellar infarcts, or strokes.
Cavaliers are predisposed to a form of congenital deafness, which is present at birth, and also to a progressive hereditary hearing loss, which usually begins during puppyhood and worsens, or progresses, until the dog is completely deaf, usually between the ages of three and five years.
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