Heart mitral valve disease (MVD) is a terminal illness which may afflict over half of all cavalier King Charles spaniels by the age of 5 years and nearly all Cavaliers by age 10 years. It is CKCSs' leading cause of death.
- More: Cavalier King Charles spaniel MVD
- Mitral valve disease breeding protocol
- A few words about pimobendan (Vetmedin)
- ACVIM cardiologists consensus statement
- Research news
- Find a cardiologist in the USA and Canada
- October 2016 -- Korean researchers find cystatin-C (Cys-C) and symmetric dimethylarginine (SDMA) as useful biomarkers of MVD progression to heart failure.
- October 2016 -- NEW BOOK: "Cavalier King Charles Spaniel: Comprehensive Care from Puppy to Senior", by Charlotte Spencer.
- October 2016 -- OUR BLOG: Pimobendan's EPIC Study: The BAD and the UGLY!
- September 2016 -- OUR BLOG: So your cavalier has a heart murmur. What do you do next? UPDATED since the EPIC Study!
- September 2016 -- The EPIC Study concludes that pimobendan can prolong pre-heart failure by 15 months in MVD-affected dogs with echo and x-ray evidence of heart enlargement.
- September 2016 -- Pimobendan significantly prolonged survival time and reoccurrence of pulmonary edema in CHF dogs.
- September 2016 -- Acupuncture successfully controls pain symptoms in a CM/SM-affected cavalier.
- September 2016 -- Brazilian vets propose using the Cardiothoracic Ratio (CTR) to measure heart enlargement.
- September 2016 -- ACVIM issues "Consensus Recommendations on the Treatment and Prevention of Uroliths in Dogs".
- September 2016 -- University of Cincinnati's FETCH~LAB offers hearing tests for dogs.
- Septemer 2016 -- Brazilian study shows the jaw disorder, temporomandibular joint dysplasia, in cavaliers.
- September 2016 -- CSU vets aptly summarize using anesthesia on MVD-affected dogs.
- August 2016 -- NEW TOPIC: Check out our new discussion of shadow chasing cavaliers.
- August 2016 -- The EPIC Trial's final report on MVD-affected dogs is expected soon.
- August 2016 -- Southeast Veterinary Neurology offers reduced cost CM/SM screening for cavaliers.
- August 2016 -- Dr. Jerold Bell's new article, "Maintaining and Improving Breeds".
- August 2016 -- Cavaliers lead list of CM/SM-affected dogs treated in England primary-care clinics, 2009-2014.
- August 2016 -- OUR BLOG: Is the University of Washington’s “Rapamycin Intervention Trial in Pet Dogs” Unethical?
- August 2016 -- NEW PAGE: Xanthinuria in Cavalier King Charles Spaniels.
- August 2016 -- NEW TOPIC: Check out our new discussion of pregnancies and gestation periods.
- August 2016 -- NEW TOPIC: Check out our new discussion of keratitis -- inflammation of the cornea due to bacteria, fungus or virus.
- August 2016 -- Cavaliers were 10% of 5-year study of bilateral surgeries for patellar luxation.
- August 2016 -- OUR BLOG: Whither the EPIC Trial's final report? Something about it smells terribly funny.
- July 2016 -- Gestation period of the CKCS is found to be shorter than that of the average canine bitch.
- July 2016 -- Dr. Simon Swift inserts wire stent to relieve pulmonic stenosis in a Havanese.
- July 2016 -- Thai veterinarians successfully relieve pulmonic stenosis in a cavalier, using valvulopasty.
- July 2016 -- Australian researchers measure blood platelet function in cavaliers with pre-heart failure MVD.
- July 2016 -- Researchers find that six brands of pregabalin are "pharmaceutically equivalent" for treating epilepsy.
- July 2016 -- Japanese researchers find serum fatty acids differ between dogs with and without MVD.
- June 2016 -- Univ. of Minnesota researchers locate a DNA mutation causing hereditary xanthinuria in cavaliers.
- June 2016 -- Ohio State University's Lynette Cole still needs cavaliers with no hearing loss for a deafness study.
- June 2016 -- Ohio State University needs cavaliers for clinical study of Chiari-like malformation and syringomyelia.
- June 2016 -- Brazilian ophthalmologisty surgeons transplant lip salivary glands to dogs' inner eye lids to cure dry eye.
- June 2016 -- USA study finds small breed dogs in heart failure live 100+ days longer if treated by cardiologists.
- June 2016 -- Studies find that most published research findings are false and that most clinical research is not useful, with clinical evidence becoming an industry advertisement tool.
- June 2016 -- Study of six cavalier pregnancies shows average ovulation periods and progesterone concentrations.
- June 2016 -- In study of 54 cavaliers, cranio-cervical junction (CCJ) abnormalities fail to predict future SM symptoms.
- June 2016 -- Cavaliers are most common and youngest victims of ischaemic stroke in study of 23 affected dogs.
- June 2016 -- Allopurinol causes xanthinuria in dogs treated for leishmaniasis.
- June 2016 -- FDA approves an appetite stimulant for ill dogs which will not eat.
- June 2016 -- Researchers may have an explanation for why ACE-inhibitors often are ineffective in treating cavaliers prior to heart failure.
- June 2016 -- Tufts study of 43 dogs (9 CKCSs) shows median survival time in Stage D MVD is nearly a year.
- May 2016 -- Study of 41 cavaliers shows that bacterial infection is an unlikely cause of PSOM in CKCSs.
- May 2016 -- UK researchers find evidence that CM in cavaliers may be due to overall brain and skull size.
- May 2016 -- UK researchers find that phantom scratching in CM/SM-affected cavaliers is due to the location and size of the syrinx.
- May 2016 -- Cavaliers have high incidence of breast tumors and low incidence of mast cell tumors, in Japanese review.
- May 2016 -- UK neurological researchers test electronic von Frey aesthesiometer to measure SM-associated neuropathic pain in cavaliers.
- May 2016 -- UK study shows SM-affected cavaliers have more blood vessels and stiffer vessel walls adjacent to lateral ventricles.
- May 2016 -- British researchers summarize episodic falling syndrome in cavaliers.
- May 2016 -- Gene researchers find a POMC gene mutation in Labradors is associated with obesity and greater food motivation.
- April 2016 -- Researchers summarize pimobendan's adverse effects reported in dogs with mild mitral valve insufficiency.
- April 2016 -- Dutch government singles out cavaliers in a study asking "Are purebreds really less healthy than crossbreeds?"
- April 2016 -- OUR BLOG: OFA finally recognizes what mitral valve disease is all about.
- April 2016 -- OUR BLOG: A Giant Leap Backwards: Some USA cavalier breeders boycott posting health test clearances on the OFA website.
- April 2016 -- UK neurologist calls for study of whether furosemide can delay syrinx growth in cavaliers.
- March 2016 -- UK orthopods report CKCSs are over-represented for medial patella luxation.
- March 2016 -- Dr. Sheila Crispin announces a study of a genetic cause of corneal dystrophy in the CKCS.
- March 2016 -- Cancerous thymus is found in 6-month old cavalier.
Veterinary specialists have designed breeding guidelines to eliminate early-onset mitral valve disease in cavalier King Charles spaniels.
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Syringomyelia (SM) is reported to be "very widespread" in the cavalier King Charles spaniel breed. Syringomyelia is a disorder of the brain and spinal cord, which may cause severe head and neck pain and possible paralysis.
- More: CKCS syringomyelia
- SM breeding protocol
- Research news
- Reduced rate MRI clinic locations
- MRI screening protocol for SM
- Find a neurologist in the USA and Canada
- Use harnesses instead of leashes for CM/SM dogs
- Estimated Breeding Values (EBVs)
- "Pedigree Dogs Exposed"
- "Pedigree Dogs Exposed - Three Years On"
Hip dysplasia reportedly afflicts up to one out of every four cavalier King Charles spaniels. It is a genetic disease which can cause the dogs pain and debilitation.
Low blood platelet counts in cavaliers usually are not a health problem. Many veterinarians are misled by low platelet counts to wrongly diagnose anemia or other serious disorders.
The size and shape of its head can cause serious breathing problems for the cavalier King Charles spaniel. Elongated soft palates, stenotic nares, everted laryngeal saccules, and laryngeal collapse are inherited developmental defects in the breed.
Cavalier King Charles spaniels appear predisposed to develop cerebellar infarcts, or strokes.
Cavaliers are predisposed to a form of congenital deafness, which is present at birth, and also to a progressive hereditary hearing loss, which usually begins during puppyhood and worsens, or progresses, until the dog is completely deaf, usually between the ages of three and five years.
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- Cerebellar Infarcts -- Brain Strokes
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